ASCL1 抗体 (AA 151-236) (Biotin)
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- 抗原 See all ASCL1 抗体
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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抗原表位
- AA 151-236
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASCL1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ASCL1
- 亚型
- IgG
- Top Product
- Discover our top product ASCL1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- 别名
- ASCL1 (ASCL1 产品)
- 背景
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Synonyms: ASH1, HASH1, MASH1, bHLHa46, Achaete-scute homolog 1, ASH-1, Class A basic helix-loop-helix protein 46, ASCL1
Background: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
- 基因ID
- 429
- UniProt
- P50553
- 途径
- Dopaminergic Neurogenesis
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