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ASCL1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects ASCL1 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 豚鼠, 犬 和 兔. It has been mentioned in 2+ publications
产品编号 ABIN2779585
发货至: 中国
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Quick Overview for ASCL1 抗体 (N-Term) (ABIN2779585)

抗原

See all ASCL1 抗体
ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

适用

  • 95
  • 49
  • 31
  • 11
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 兔

宿主

  • 97
  • 6
  • 4
兔

克隆类型

  • 100
  • 7
多克隆

标记

  • 49
  • 10
  • 8
  • 8
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ASCL1 antibody is un-conjugated

应用范围

  • 79
  • 48
  • 32
  • 13
  • 13
  • 12
  • 11
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 23
    • 15
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    ASCL1 Antibody - N-terminal region

    序列

    QSAQQQQQQQ QQQQQAPQLR PAADGQPSGG GHKSAPKQVK RQRSSSPELM

    预测反应

    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ASCL1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32355-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Suozzi, Malatesta, Zancanaro: "Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle." in: Journal of anatomy, Vol. 214, Issue 6, pp. 956-62, (2009) (PubMed).

    Vias, Massie, East, Scott, Warren, Zhou, Nikitin, Neal, Mills: "Pro-neural transcription factors as cancer markers." in: BMC medical genomics, Vol. 1, pp. 17, (2008) (PubMed).

  • 抗原

    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

    别名

    ASCL1

    背景

    Background Information: ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.

    Gene Name: Achaete-scute complex homolog 1 (Drosophila)

    Alternative Symbols: ASH1, HASH1, MASH1, bHLHa46

    Protein Name: Achaete-scute homolog 1

    分子量

    25 kDa

    基因ID

    429

    NCBI登录号

    NP_004307

    UniProt

    P50553

    途径

    Dopaminergic Neurogenesis
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