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ASCL1 抗体 (N-Term)

ASCL1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779585
发货至: 中国
  • 抗原 See all ASCL1 抗体
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    抗原表位
    • 16
    • 15
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 79
    • 43
    • 26
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 兔
    宿主
    • 79
    • 5
    • 2
    克隆类型
    • 81
    • 5
    多克隆
    标记
    • 39
    • 10
    • 8
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCL1 antibody is un-conjugated
    应用范围
    • 73
    • 55
    • 22
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    QSAQQQQQQQ QQQQQAPQLR PAADGQPSGG GHKSAPKQVK RQRSSSPELM
    预测反应
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ASCL1
    Top Product
    Discover our top product ASCL1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 236 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Suozzi, Malatesta, Zancanaro: "Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle." in: Journal of anatomy, Vol. 214, Issue 6, pp. 956-62, (2009) (PubMed).

    Vias, Massie, East, Scott, Warren, Zhou, Nikitin, Neal, Mills: "Pro-neural transcription factors as cancer markers." in: BMC medical genomics, Vol. 1, pp. 17, (2008) (PubMed).

  • 抗原
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    别名
    ASCL1 (ASCL1 产品)
    别名
    ASH1 antibody, HASH1 antibody, MASH1 antibody, bHLHa46 antibody, AI225900 antibody, Mash1 antibody, ASCL1 antibody, Zash-1a antibody, ash antibody, asha antibody, id:ibd5085 antibody, im:7138587 antibody, si:dkey-264k15.2 antibody, zash1a antibody, zasha antibody, Xash1 antibody, ascl1-A antibody, Zash-1b antibody, ashb antibody, zashb antibody, achaete-scute family bHLH transcription factor 1 antibody, achaete-scute family bHLH transcription factor 1a antibody, achaete-scute family bHLH transcription factor 1 L homeolog antibody, achaete-scute complex homolog 1 antibody, achaete-scute family bHLH transcription factor 1b antibody, ASCL1 antibody, Ascl1 antibody, ascl1a antibody, ascl1.L antibody, LOC100220505 antibody, ascl1b antibody
    背景
    ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
    Alias Symbols: ASH1, HASH1, MASH1, bHLHa46
    Protein Interaction Partner: MEF2D, MEF2C, MEF2A, NEUROG2, UBQLN1, EP300, TCF4, BMP2, ASCL1,
    Protein Size: 236
    分子量
    25 kDa
    基因ID
    429
    NCBI登录号
    NM_004316, NP_004307
    UniProt
    P50553
    途径
    Dopaminergic Neurogenesis
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