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ASCL1 抗体 (AA 151-236)

This anti-ASCL1 antibody is a 兔 多克隆 antibody detecting ASCL1 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN738471
发货至: 中国

Quick Overview for ASCL1 抗体 (AA 151-236) (ABIN738471)

抗原

See all ASCL1 抗体
ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

适用

  • 82
  • 51
  • 32
  • 9
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 82
  • 5
  • 5

克隆类型

  • 87
  • 5
多克隆

标记

  • 44
  • 9
  • 7
  • 7
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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This ASCL1 antibody is un-conjugated

应用范围

  • 74
  • 51
  • 29
  • 12
  • 12
  • 10
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 11
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-236

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ASCL1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Misra, Luo, Li, Matise, Xiang: "Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord." in: Development (Cambridge, England), Vol. 141, Issue 1, pp. 187-98, (2014) (PubMed).

  • 抗原

    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

    别名

    ASCL1

    背景

    Synonyms: ASH1, HASH1, MASH1, bHLHa46, Achaete-scute homolog 1, ASH-1, Class A basic helix-loop-helix protein 46, ASCL1

    Background: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

    基因ID

    429

    UniProt

    P50553

    途径

    Dopaminergic Neurogenesis
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