Serotonin Receptor 1A 抗体 (AA 301-400)
Quick Overview for Serotonin Receptor 1A 抗体 (AA 301-400) (ABIN738006)
抗原
See all Serotonin Receptor 1A (HTR1A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from rat 5-HTR1A
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes." in: Life sciences, Vol. 293, pp. 120335, (2022) (PubMed).
: "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Vol. 27, Issue 11, pp. 3355-3364, (2016) (PubMed).
: "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice." in: Translational psychiatry, Vol. 6, Issue 6, pp. e836, (2016) (PubMed).
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Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes." in: Life sciences, Vol. 293, pp. 120335, (2022) (PubMed).
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- Serotonin Receptor 1A (HTR1A)
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别名
- 5-HTR1A
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背景
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Synonyms: 5HT1A, RAT5HT1A, 5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A, Htr1a
Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
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基因ID
- 24473
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UniProt
- P19327
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途径
- JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
抗原
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