NADPH Oxidase 4 抗体 (AA 81-180)
Quick Overview for NADPH Oxidase 4 抗体 (AA 81-180) (ABIN737526)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-180
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse Nox-4
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury." in: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).
: "Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase." in: Urology, Vol. 83, Issue 2, pp. 510.e1-7, (2014) (PubMed).
: "
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CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury." in: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).
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- NADPH Oxidase 4 (NOX4)
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别名
- NADPH oxidase 4
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背景
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Synonyms: AI64821, NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, Superoxide-generating NADPH oxidase 4, Nox4, Renox
Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
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基因ID
- 50490
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UniProt
- Q9JHI8
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途径
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
抗原
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