MERTK 抗体 (pTyr749, pTyr753, pTyr754)
Quick Overview for MERTK 抗体 (pTyr749, pTyr753, pTyr754) (ABIN7795874)
抗原
See all MERTK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr749, pTyr753, pTyr754
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原理
- Anti-MerTK (Tyr749/753/754) Antibody
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特异性
- Specific for the ~160 kDa MerTK protein phosphorylated at Tyr749/753/754. The immunolabeling is completely eliminated by treatment with λ-phosphatase. Due to post-translational modifications of the Mer protein, a significant shift in molecular weight is seen from the predicted molecular weight of 110 kDa. For optimal results immunoprecipitation is recommended due to the 91 % homology of the related receptor tyrosine kinase, Axl, that runs at ~140 kDa.
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Our MerTK Tyr749/753/754 rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects MerTK Tyr749/753/754 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
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纯化方法
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr749/753/754 of human MerTK, conjugated to keyhole limpet hemocyanin (KLH).
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亚型
- IgG
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应用备注
- 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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有效期
- 12 months
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- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
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别名
- MerTK
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背景
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Synonyms: c MER antibody, c mer proto oncogene tyrosine kinase antibody, c-mer antibody, cMER antibody, cmer protooncogene tyrosine kinase antibody, Eyk antibody, MER antibody, MER receptor tyrosine kinase antibody, MERK antibody, MERPEN antibody, Mertk antibody, MERTK c-mer proto-oncogene tyrosine kinase antibody, MERTK_HUMAN antibody, MGC133349 antibody, nmf12 antibody, Nyk antibody, Proto oncogene tyrosine protein kinase MER antibody, Proto oncogene tyrosine protein kinase MER precursor antibody, Proto-oncogene c-Mer antibody, Receptor tyrosine kinase MerTK antibody, RP38 antibody, STK kinase antibody, Tyrosine-protein kinase Mer antibody
Description Logic: Our MerTK Tyr749/753/754 rabbit polyclonal phosphospecific primary antibody is produced . It detects MerTK Tyr749/753/754 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
Gene Name Alternatives: MERTK
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分子量
- 160 kDa
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基因ID
- 10461
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UniProt
- Q12866
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途径
- RTK signaling
抗原
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