RPA2
适用: 小鼠
WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
WB,11,000
限制
仅限研究用
状态
Liquid
浓度
1000 μg/mL
缓冲液
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
2 - 8 °C
有效期
12 months
抗原
RPA2
(Replication Protein A2, 32kDa (RPA2))
别名
RPA32
背景
Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32 kDa (RPA2), and 14 kDa (RPA3). RPA2, the 32 kDa subunit, is phosphorylated by the cdc2 family of kinases when cells enter S-phase and in response to DNA damage by ATM, ATR, and DNA-PK.