Recombinant BRCA1 抗体 (AA 525-575)
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北京 101111
Quick Overview for Recombinant BRCA1 抗体 (AA 525-575) (ABIN7795735)
抗原
See all BRCA1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 525-575
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原理
- Rabbit anti-BRCA1 Recombinant Monoclonal Antibody [BLR319M]
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纯化方法
- Purified
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免疫原
- Between 525 and 575
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亚型
- IgG
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应用备注
- IP,6 μL/mg lysate,WB,11000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- BRCA1 (Breast Cancer 1 (BRCA1))
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别名
- BRCA1
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背景
- BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.
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基因ID
- 12189
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UniProt
- P48754
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途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
抗原
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