Recombinant EGFR 抗体 (AA 1100-1150)
Our Local Distributor
北京 101111
Quick Overview for Recombinant EGFR 抗体 (AA 1100-1150) (ABIN7795640)
抗原
See all EGFR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1100-1150
-
原理
- Rabbit anti-EGFR Recombinant Monoclonal Antibody [BLR251L]
-
纯化方法
- Purified
-
免疫原
- Between 1100 and 1150
-
亚型
- IgG
-
-
-
-
应用备注
- ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,20 μL/mg lysate ,WB,11000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 200 μg/mL
-
缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- 2 - 8 °C
-
有效期
- 12 months
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
别名
- EGFR
-
背景
- The epidermal growth factor receptor (EGFR) is a membrane spanning tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family such as TGF-alpha, amphiregulin, betacellulin, epiregulin and heparin-binding EGF-like growth factor. Upon ligand binding, the EGFR homodimerizes or heterodimerizes with other ErbB receptor family members and tranduces a downstream signal via the ras-raf-mitogen activated protein kinase pathway or the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Signals from the EGFR function to influence cell proliferation, differentiation, and development.
-
基因ID
- 1956
-
UniProt
- P00533
-
途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
-