SERPINB2 抗体 (AA 131-230) (FITC)
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北京 101111
Quick Overview for SERPINB2 抗体 (AA 131-230) (FITC) (ABIN735570)
抗原
See all SERPINB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-230
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PAI-2
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亚型
- IgG
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anti-Plasminogen Activator Inhibitor 2 (SERPINB2) antibody
SERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Center) antibodySERPINB2 适用: 人, 小鼠 WB, IP, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A10 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) antibodySERPINB2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 293-389) antibodySERPINB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) antibodySERPINB2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13985 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Internal Region) antibodySERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) antibodySERPINB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 170-393) antibodySERPINB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
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别名
- Pai-2/Serpinb2
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物质类
- Amino Acid
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背景
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Synonyms: Serpin B2, Serpinb2, SerpinB2, plasminogen activator inhibitor 2, HsT1201, Monocyte Arg serpin, Monocyte Arg-serpin, PAI2A, PAI, PAI-2, PAI 2, PAI2, Placental plasminogen activator inhibitor, PAI2_RAT, PLANH2, Plasminogen activator inhibitor 2, Plasminogen activator inhibitor 2 type A, Serpin peptidase inhibitor clade B ovalbumin member 2, Urokinase inhibitor.
Background: SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin. SerpinB2 is made by many cell types, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein. SerpinB2 is found in saliva, secreted by gingival fibroblasts, and in the skin. SerpinB2 levels are elevated in serum during pregnancy, and in leukemia, breast cancer and ovarian cancer, although it was lowered in some cancers.A shorter SerpinB2 isoform of 382 amino acids, has been reported, with a predicted mass of 43.1 kDa and a pI of 5.69. The shorter form has a deletion just after the start of the mature protein, but it is unclear what the relative production and distribution is for the shorter sequence.
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基因ID
- 5055
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途径
- Autophagy
抗原
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