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CCKBR 抗体 (AA 301-400)

This anti-CCKBR antibody is a 兔 多克隆 antibody detecting CCKBR in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN734318
发货至: 中国

Quick Overview for CCKBR 抗体 (AA 301-400) (ABIN734318)

抗原

See all CCKBR 抗体
CCKBR (Cholecystokinin B Receptor (CCKBR))

适用

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小鼠, 大鼠

宿主

  • 44
  • 1
  • 1

克隆类型

  • 45
  • 1
多克隆

标记

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  • 1
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  • 1
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This CCKBR antibody is un-conjugated

应用范围

  • 30
  • 12
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  • 4
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  • 3
  • 2
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  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 5
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    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 301-400

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Cow,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Gastrin receptor

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Eberhard, Kirkeby, Hansen, Cayé-Thomasen: "Neurotransmitter and neurotransmitter receptor expression in the saccule of the human vestibular system." in: Progress in neurobiology, Vol. 212, pp. 102238, (2022) (PubMed).

    Liu, Banerjee, Herring, Attalla, Hu, Xu, Shao, Simmons, Dadi, Wang, Jacobson, Liu, Hodges, Lau, Gu: "Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity." in: Developmental cell, Vol. 48, Issue 1, pp. 49-63.e7, (2019) (PubMed).

    Mohammad, Ozaki, Takeuchi, Unno, Yamoto, Morioka, Takiguchi, Ikeda: "Functional compensation between cholecystokinin-1 and -2 receptors in murine paraventricular nucleus neurons." in: The Journal of biological chemistry, Vol. 287, Issue 47, pp. 39391-401, (2012) (PubMed).

    Kalsheker, Hodgson, Watkins, White, Morrison, Stockley: "Deoxyribonucleic acid (DNA) polymorphism of the alpha 1-antitrypsin gene in chronic lung disease." in: British medical journal (Clinical research ed.), Vol. 294, Issue 6586, pp. 1511-4, (1987) (PubMed).

  • 抗原

    CCKBR (Cholecystokinin B Receptor (CCKBR))

    别名

    Gastrin receptor/GASR/CCKBR

    背景

    Synonyms: GASR, CCK-B, CCK2R, Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R, CCKBR, CCKRB

    Background: Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.

    基因ID

    887

    UniProt

    P32239

    途径

    Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour
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