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CCR3 抗体 (FineTest®647)

This anti-CCR3 antibody is a 小鼠 单克隆 antibody detecting CCR3 in FACS. Suitable for 人.
产品编号 ABIN7675394
发货至: 中国

Quick Overview for CCR3 抗体 (FineTest®647) (ABIN7675394)

抗原

See all CCR3 抗体
CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CCR3 antibody is conjugated to FineTest®647

应用范围

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Flow Cytometry (FACS)

克隆位点

5E8
  • 原理

    FineTest®647 Anti-Human CD193/CCR3 Antibody

    亚型

    IgG2b, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

    别名

    CD193

    背景

    Synonyms: MIP1-alpha receptor like-2eotaxin receptor|C-C chemokine receptor type 3|CC CKR3|CCR|CCR3

    Background: CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

    分子量

    0

    基因ID

    1232

    UniProt

    P51677
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