IRAK3 抗体 (AA 428-596)
Quick Overview for IRAK3 抗体 (AA 428-596) (ABIN7673412)
抗原
See all IRAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 428-596
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原理
- IRAK3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 428-596aa
Immunogen: IRAK3
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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别名
- IRAK3
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背景
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Synonyms: Interleukin-1 receptor-associated kinase 3 (IRAK-3)|IL-1 receptor-associated kinase M (IRAK-M)|Inactive IL-1 receptor-associated kinase 3|IRAK3
Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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分子量
- 68 kDa
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基因ID
- 11213
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UniProt
- Q9Y616
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途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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