IRAK3 抗体 (AA 491-540)
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北京 101111
Quick Overview for IRAK3 抗体 (AA 491-540) (ABIN1534222)
抗原
See all IRAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 491-540
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原理
- IRAK-M Antibody
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特异性
- IRAK-M Polyclonal Antibody detects endogenous levels of IRAK-M protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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别名
- IRAK3
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背景
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Synonyms: IRAK3, Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M
Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
Gene Name: IRAK3
Protein Name: Interleukin-1 receptor-associated kinase 3
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分子量
- 67 kDa
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基因ID
- 11213
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OMIM
- 604459
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UniProt
- Q9Y616
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途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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