CREB1 抗体
Quick Overview for CREB1 抗体 (ABIN7672988)
抗原
See all CREB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CREB1 antibody
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纯化方法
- protein A+G purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- cAMP responsive element binding protein 1
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亚型
- IgG1
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
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别名
- CREB1
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背景
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Synonyms: Cyclic AMP-responsive element-binding protein 1|CREB-1|cAMP-responsive element-binding protein 1|CREB1|CREB
Background: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element(CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
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分子量
- 43-46 kDa
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基因ID
- 1385
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UniProt
- P16220
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
抗原
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