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Beclin 1 抗体

This anti-Beclin 1 antibody is a 小鼠 单克隆 antibody detecting Beclin 1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7672911
发货至: 中国

Quick Overview for Beclin 1 抗体 (ABIN7672911)

抗原

See all Beclin 1 (BECN1) 抗体
Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

适用

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人, 小鼠, 大鼠

宿主

  • 139
  • 41
  • 2
  • 1
小鼠

克隆类型

  • 137
  • 46
单克隆

标记

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This Beclin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

1G5
  • 原理

    BECN1 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 141-450

    Immunogen: beclin 1, autophagy related

    亚型

    IgG1
  • 应用备注

    WB: 1:500 - 1:5000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

    别名

    BECN1

    背景

    Synonyms: Beclin-1|Coiled-coil myosin-like BCL2-interacting protein|Protein GT197|Beclin-1-C 35 kDa|Beclin-1-C 37 kDa|BECN1|GT197

    Background: Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

    分子量

    60 kDa

    基因ID

    8678

    UniProt

    Q14457

    途径

    Autophagy
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