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Beclin 1 抗体 (AA 1-354)

BECN1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030155
发货至: 中国
  • 抗原 See all Beclin 1 (BECN1) 抗体
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    抗原表位
    • 16
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    • 9
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    • 9
    • 8
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 1-354
    适用
    • 196
    • 88
    • 72
    • 10
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 166
    • 33
    • 2
    克隆类型
    • 166
    • 35
    多克隆
    标记
    • 91
    • 17
    • 15
    • 14
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    • 4
    • 4
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    • 4
    • 4
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    This Beclin 1 antibody is un-conjugated
    应用范围
    • 141
    • 94
    • 57
    • 34
    • 29
    • 26
    • 25
    • 22
    • 19
    • 13
    • 13
    • 4
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 1-354) was used as the immunogen for this Beclin 1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product BECN1 Primary Antibody
  • 应用备注
    Titration of the Beclin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Beclin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    别名
    Beclin 1 (BECN1 产品)
    别名
    beclin-1 antibody, atg6 antibody, vps30 antibody, beclin1 antibody, Beclin-1 antibody, becn1 antibody, zgc:73097 antibody, ATG6 antibody, VPS30 antibody, 4921513J16Rik antibody, 5430417M23Rik antibody, Atg6 antibody, beclin 1 antibody, beclin 1, autophagy related antibody, beclin 1 protein antibody, beclin-1 antibody, beclin family protein antibody, beclin 1, autophagy related L homeolog antibody, BECN1 antibody, becn1 antibody, atg6 antibody, CpipJ_CPIJ011087 antibody, PTRG_07825 antibody, SJAG_01876 antibody, Becn1 antibody, becn1.L antibody
    背景
    Beclin 1, also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene. Beclin 1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. This gene participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Schizophrenia is associated with low levels of the protein in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death. It has been found that Beclin 1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30, and in human MCF7 breast carcinoma cells.
    基因ID
    8678
    途径
    Autophagy
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