Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
有效期
12 months
抗原
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
别名
VEGF R2/KDR
背景
VEGFR2,CD309,FLK1,Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.