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Ret Proto-Oncogene 抗体

This anti-Ret Proto-Oncogene antibody is a 兔 多克隆 antibody detecting Ret Proto-Oncogene in ELISA. Suitable for 人.
产品编号 ABIN7670736
发货至: 中国

Quick Overview for Ret Proto-Oncogene 抗体 (ABIN7670736)

抗原

See all Ret Proto-Oncogene (RET) 抗体
Ret Proto-Oncogene (RET)

适用

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宿主

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克隆类型

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多克隆

标记

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This Ret Proto-Oncogene antibody is un-conjugated

应用范围

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ELISA
  • 原理

    RET Polyclonal Antibody(Capture/Detector)

    纯化方法

    Antigen Affinity Purification

    免疫原

    Recombinant Human RET protein expressed by Mammalian

    亚型

    IgG
  • 应用备注

    ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    Ret Proto-Oncogene (RET)

    别名

    RET

    背景

    Proto-oncogene tyrosine-protein kinase receptor Ret,Cadherin family member 12,Proto-oncogene c-Ret,This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. RET (Ret Proto-Oncogene) is a Protein Coding gene. Diseases associated with RET include Multiple Endocrine Neoplasia Iia and Medullary Thyroid Carcinoma, Familial. Among its related pathways are RET signaling and Innate Immune System. GO annotations related to this gene include calcium ion binding and protein kinase activity. An important paralog of this gene is PDGFRB.

    UniProt

    P07949

    途径

    RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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