IL6RA 抗体
This 山羊 多克隆 antibody specifically detects IL6RA in ELISA. It exhibits reactivity toward 小鼠.
产品编号 ABIN7670672
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for IL6RA 抗体 (ABIN7670672)
抗原
See all IL6RA 抗体
IL6RA
(Interleukin 6 Receptor, alpha (IL6RA))
适用
小鼠
宿主
山羊
克隆类型
多克隆
标记
This IL6RA antibody is un-conjugated
应用范围
ELISA
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原理
- IL-6R alpha Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Mouse IL-6R alpha ra Protein expressed by Mammalian
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亚型
- IgG
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anti-Interleukin 6 Receptor, alpha (IL6RA) (AA 351-460) antibody
IL6RA 适用: 人, 小鼠, 大鼠 FACS, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor, alpha (IL6RA) (Internal Region) antibodyIL6RA 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- IL6RA (Interleukin 6 Receptor, alpha (IL6RA))
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别名
- IL-6R alpha
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背景
- InterLeukin-6 receptor subunit aLpha,IL-6 receptor subunit aLpha,IL-6R subunit aLpha,IL-6R-aLpha,IL-6RA,IL-6R 1,Part of the receptor for interleukin 6. Binds to Il6 with low affinity,but does not transduce a signal. Signal activation necessitate an association with Il6ST. Activation leads to the regulation of the immune response,acute-phase reactions and hematopoiesis. The interaction with membrane-bound Il6R and Il6ST stimulates 'classic signaling',the restricted expression of the Il6R limits classic Il6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of Il6 and soluble Il6R to Il6ST stimulates 'trans-signaling'. Alternatively,'cluster signaling' occurs when membrane-bound Il6:Il6R complexes on transmitter cells activate Il6ST receptors on neighboring receiver cells.
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UniProt
- P22272
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途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
抗原
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