IL-18 抗体
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北京 101111
Quick Overview for IL-18 抗体 (ABIN7670661)
抗原
See all IL-18 (IL18) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IL-18/IL-1F4 Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human IL-18/IL-1F4 protein expressed by E.coli
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- IL-18 (IL18) (Interleukin 18 (IL18))
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别名
- IL-18/IL-1F4
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背景
- IL18,IL-18, IGIF, IL1F4,Iboctadekin,Interferon gamma-inducing factor,InterLeukin-1 gamma (IL-1 gamma),Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to Il18R1 and Il18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with Il12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
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UniProt
- Q14116
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途径
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
抗原
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