IGFBP5 抗体
Our Local Distributor
北京 101111
Quick Overview for IGFBP5 抗体 (ABIN7670643)
抗原
See all IGFBP5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- IGFBP-5 Monoclonal Antibody(Detector)
-
纯化方法
- Protein A/G Purification
-
免疫原
- Recombinant Human IGFBP-5 protein expressed by E.coli
-
亚型
- IgG2b
-
-
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 68-167) antibody
IGFBP5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) antibodyIGFBP5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 25-271) antibodyIGFBP5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) antibodyIGFBP5 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 101-200) antibodyIGFBP5 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 27-248) antibodyIGFBP5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 27-248) antibodyIGFBP5 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 87-121) antibodyIGFBP5 适用: 人 WB 宿主: 兔 Polyclonal RB54635 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 1-272) antibodyIGFBP5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 111-160) antibodyIGFBP5 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 绵羊, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- ELISA Detector 0.1-0.4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Sterile PBS , pH 7.4
-
储存液
- Without preservative
-
注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
-
有效期
- 12 months
-
-
- IGFBP5 (Insulin-Like Growth Factor Binding Protein 5 (IGFBP5))
-
别名
- IGFBP-5
-
背景
- IBP5,IGFBP5,IBP-5,IGF-binding protein 5,IGFBP-5,InsuLin-Like growth factor-binding protein 5,The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues,which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBPs,including glycosylation,phosphorylation and proteolysis,have been shown to modify the affinities of the binding proteins to IGF. Mouse IGFBP-5 cDNA encodes a 271 amino acid (aa) residue precursor protein with a putative 19 aa residue signal peptide that is processed to generate the 252 aa residue mature protein. Mouse,human and rat IGFBP-5 share 97 % identity. IGFBP-5 is expressed by fibroblasts,myoblasts and osteoblasts,making it the predominant IGFBP found in bone extracts. IGFBP-5 has a strong affinity for hydroxyapatite,allowing it to bind to bone cells. When bound to extracelluar matrix,IGFBP-5 is protected from proteolysis and potentiates IGF activity,but when it is soluble,IGFBP-5 is cleaved to a biologically inactive 21 kDa fragment.
-
UniProt
- P24593
-
途径
- WNT signaling, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
抗原
-
