Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
有效期
12 months
抗原
HYAL1
(Hyaluronidase-1 (HYAL1))
别名
Hyaluronidase 1/HYAL1
背景
Hyaluronic Lase,yaluronic acid (HA) is a glycosaminoglycan that is believed to have numerous important biologic functions,including modulation of cell proliferation,migration,and differentiation,as well as the regulation of extracellular water and protein homeostasis. It is also an integral structural component of cartilage and other tissues and acts as a lubricant in joints. Hyaluronidases are a family of enzymes that catalyse the degradation of HA. In humans,there are five functional hyaluronidases: HYAL1,HYAL2,HYAL3,HYAL4 and HYAL5 (also known as SPAM1 or PH-20), plus a pseudogene,HYAL6 (also known as HYALP1). HYAL-1 is present in many tissues and is predominantly found in the plasma and urine (PMID: 16600643). In addition to its function in normal cellular hyaluronan turnover,human HYAL-1 is implicated in cancer proliferation,angiogenesis,and inflammatory diseases