Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
≥ 1 mg/mL
缓冲液
Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
储存液
Azide free
注意事项
avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
有效期
12 months
抗原
SLAMF1
(Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
别名
CD150
背景
SLAM family member,SLAMF,CD 150,CD150,CD150 antigen,Signaling lymphocytic activation molecule,SLAM family member 1,Slam,Slamf1, IPO-3,CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.