CD40 抗体
Quick Overview for CD40 抗体 (ABIN7670160)
抗原
See all CD40 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Mouse CD40 Antibody[1C10]
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内毒素水平
- Low Endotoxin
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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储存液
- Azide free
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注意事项
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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有效期
- 12 months
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- CD40
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别名
- CD40
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背景
- Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5,CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature mCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 90 aa cytoplasmic domain . CD40 is expressed on B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells and several tumor cell lines.
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UniProt
- P27512
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途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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