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CD40 抗体

This anti-CD40 antibody is a 大鼠 单克隆 antibody detecting CD40 in FACS. Suitable for 小鼠.
产品编号 ABIN7670160
发货至: 中国

Quick Overview for CD40 抗体 (ABIN7670160)

抗原

See all CD40 抗体
CD40

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD40 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

1C10
  • 原理

    AF/LE Purified Anti-Mouse CD40 Antibody[1C10]

    内毒素水平

    Low Endotoxin

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

    储存液

    Azide free

    注意事项

    avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    有效期

    12 months
  • 抗原

    CD40

    别名

    CD40

    背景

    Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5,CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature mCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 90 aa cytoplasmic domain . CD40 is expressed on B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells and several tumor cell lines.

    UniProt

    P27512

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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