ErbB2/Her2 抗体
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北京 101111
Quick Overview for ErbB2/Her2 抗体 (ABIN8062509)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD340 Antibody[chA21]
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亚型
- IgG2a, kappa
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 适用: 人, 小鼠, 大鼠, 犬, 猴, 马, Pig, Cow, 兔, Hamster, Avian, Cat, 小鸡, 驴, 山羊, 豚鼠, 绵羊 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 适用: 人 IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 适用: 人 IHC 宿主: 小鼠 Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (N-Term) antibodyErbB2/Her2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (Extracellular Domain) antibodyErbB2/Her2 适用: 人 IF, ELISA, FACS 宿主: 小鼠 Monoclonal HRB2-282 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1196) antibodyErbB2/Her2 适用: 人 WB, IF, DB 宿主: 兔 Polyclonal RB40085 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze / thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
- CD340
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背景
- TKR,ERBB,erb-b2 receptor tyrosine kinase,Receptor tyrosine-protein kinase erbB,Tyrosine kinase-type cell surface receptor HER,HER2/ErbB,HER,MLN,ERBB2,CD340,HER-2,HER-2/neu,HER2,MLN 19,NEU,NGL,TKR1,erb-b2 receptor tyrosine kinase 2,HER2/ErbB2,MLN19,Metastatic lymph node gene 19 protein,p185,Proto-oncogene Neu,Receptor tyrosine-protein kinase erbB-2,Tyrosine kinase-type cell surface receptor HER2, Neu, erb-B2,CD340,erb-b2 receptor tyrosine kinase 2,HER2,HER-2,HER-2/neu,MLN 19,MLN19,NGL,TKR1,C erb B2/neu protein,CD340 antigen,Cerb B2/neu protein,CerbB2,ENV,ENVW,Erb b2 receptor tyrosine kinase 2,ERVWE1,HER 2,HER 2/NEU,Herstatin,HERV7Q,HERV-7q,HERVW,HERVWENV,HERV-W-ENV,Human epidermal growth factor receptor 2,NEU proto oncogene,neuro/glioblastoma derived oncogene homolog,neuro/glioblastoma derived oncogene homolog (avian),Neuroblastoma/glioblastoma derived oncogene homolog,p185erbB2,Proto-oncogene c-ErbB-2,Tyrosine kinase type cell surface receptor HER2,V erb b2 avian erythroblastic leukemia viral oncogene homolog 2,V erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog),V erb b2 avian erythroblastic leukemia viral oncoprotein 2,V erb b2 erythroblastic leukemia viral oncogene homolog 2,Verb b2 erythroblastic leukemia viral oncogene homolog 2,ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1, heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.
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UniProt
- P04626
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
抗原
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