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CTLA4 抗体

The 小鼠 单克隆 anti-CTLA4 antibody (Clone BNI3) (ABIN7670048) specifically detects CTLA4 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7670048
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CTLA4 抗体 (ABIN7670048)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

BNI3
  • 原理

    Purified Anti-Human CD152 Antibody[BNI3]

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze / thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CD152

    背景

    GRD,ALPS,IDDM,Cytotoxic T-lymphocyte protein,Cytotoxic T-lymphocyte-associated antigen,Cytotoxic T-Lymphocyte-Associated Protein,CELIAC,CTLA4,ALPS5,CD,CD152,CELIAC3,CTLA-4,GRD4,GSE,IDDM12,Cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,Cytotoxic T-Lymphocyte-Associated Protein 4,This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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