This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
avoid freeze / thaw cycles.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
有效期
12 months
抗原
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
别名
CD152
背景
GRD,ALPS,IDDM,Cytotoxic T-lymphocyte protein,Cytotoxic T-lymphocyte-associated antigen,Cytotoxic T-Lymphocyte-Associated Protein,CELIAC,CTLA4,ALPS5,CD,CD152,CELIAC3,CTLA-4,GRD4,GSE,IDDM12,Cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,Cytotoxic T-Lymphocyte-Associated Protein 4,This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.