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CCR5 抗体

This anti-CCR5 antibody is a 小鼠 单克隆 antibody detecting CCR5 in FACS. Suitable for 人.
产品编号 ABIN7670043
发货至: 中国

Quick Overview for CCR5 抗体 (ABIN7670043)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

  • 156
  • 47
  • 41
  • 9
  • 2
  • 1
  • 1
  • 1

宿主

  • 109
  • 42
  • 13
  • 3
  • 1
  • 1
小鼠

克隆类型

  • 107
  • 55
  • 4
单克隆

标记

  • 91
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  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This CCR5 antibody is un-conjugated

应用范围

  • 92
  • 73
  • 67
  • 26
  • 24
  • 21
  • 13
  • 13
  • 13
  • 12
  • 10
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

RoAb13
  • 原理

    Purified Anti-Human CD195 Antibody[RoAb13]

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze / thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CD195

    背景

    IDDM,CCCKR,CMKBR,CC-CKR,CKR,CCR,CKR5,CCR-5,CD195,CKR-5,CCCKR5,CMKBR5,IDDM22,CC-CKR-5,CCR5,CCCKR5,CC-CKR-5,CCR-5,CD195,CKR-5,CMKBR5,IDDM22,This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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