This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
avoid freeze / thaw cycles.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
有效期
12 months
抗原
CCR3
(Chemokine (C-C Motif) Receptor 3 (CCR3))
别名
CD193
背景
CKR,B-lymphocyte antigen CD,MIP1-alpha receptor like,Differentiation antigen CD,C-C chemokine receptor type,Neural cell adhesion molecule,CMKBR,N-CAM,CC-CKR,CC CKR,CCR3,CC-CKR-3,CD193,CKR3,CMKBR3,B-lymphocyte antigen CD19,C-C chemokine receptor type 3,CC CKR3,CCR,Cd19,Differentiation antigen CD19,eotaxin receptor,MIP1-alpha receptor like-2,NCAM,NCAM1,NCAM-1,N-CAM-1,Neural cell adhesion molecule 1,C-C CKR-3,C-C motif chemokine receptor 3,CD_antigen: CD193,cluster of differentiation 193,Eosinophil eotaxin receptor,The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.