YBX1 抗体 (CF®640R)
Quick Overview for YBX1 抗体 (CF®640R) (ABIN7662065)
抗原
See all YBX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)(YBX1/2430), CF640R conjugate
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产品特性
- The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19,000 full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length YBX1 protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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别名
- Y-box Binding Protein 1
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背景
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Synonyms: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1
Gene Symbol: YBX1
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分子量
- 36 kDa
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基因ID
- 4904
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UniProt
- P67809
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途径
- Regulation of Muscle Cell Differentiation
抗原
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