UPK1A 抗体 (AA 114-173) (CF®405S)
Quick Overview for UPK1A 抗体 (AA 114-173) (CF®405S) (ABIN7661613)
抗原
See all UPK1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 114-173
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原理
- Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2921), CF405S conjugate
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产品特性
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Urinary Bladder.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- UPK1A (Uroplakin 1a (UPK1A))
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别名
- Uroplakin 1A
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背景
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Synonyms: UP1A, UPIA, UPKA, TSPAN21
Gene Symbol: UPK1A
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分子量
- 29 kDa
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基因ID
- 11045
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UniProt
- O00322
抗原
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