Tyrosinase-Related Protein 1 抗体 (CF®740)
Quick Overview for Tyrosinase-Related Protein 1 抗体 (CF®740) (ABIN7661517)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TRP1 (Tyrosinase Related Protein 1) (TA99 + TYRP1/807), CF740 conjugate
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产品特性
- This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- SK-MEL-23 cells (TA99), Recombinant full-length human TYRP1 protein (TYRP1/807)
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亚型
- IgG
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anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, Cow, 豚鼠, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 兔 Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼, 猴, 小鸡, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Monoclonal TYRP1-1564R unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Not suitable for FFPE sections. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30 cells or Melanoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- TRP1
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背景
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Synonyms: 5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP
Gene Symbol: TYRP1
Tissue Expression: Melanocytes
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分子量
- 75 kDa
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基因ID
- 7306
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UniProt
- P17643
抗原
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