SUMO1 抗体 (CF®740)
Quick Overview for SUMO1 抗体 (CF®740) (ABIN7660011)
抗原
See all SUMO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SUMO-1(SUMO1/1188), CF740 conjugate
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产品特性
- This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human SUMO1 protein
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亚型
- IgG1, kappa
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anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibody
SUMO1 适用: 人, 大鼠, 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibodySUMO1 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibodySUMO1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibodySUMO1 适用: 人, 大鼠 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal SM1-495 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (N-Term) antibodySUMO1 适用: 人, 大鼠, 小鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibodySUMO1 适用: 人 WB, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30), (N-Term) antibodySUMO1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB0629 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 55-86) antibodySUMO1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 52-79) antibodySUMO1 适用: 人 WB, IF, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30) antibodySUMO1 适用: 人 WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Predicted to show broad species reactivity. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Breast carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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别名
- SUMO 1
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背景
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Synonyms: GAP-modifying protein 1, GMP1, OFC10, PIC1, SENP2, Sentrin 1, Small ubiquitin-related modifier 1, SMT3, SMT3 suppressor of mif two 3 homolog 1, SMT3C, SMT3H3, Ubiquitin homology domain protein PIC1, Ubiquitin Like 1, Ubiquitin like protein UBL1
Gene Symbol: SUMO1
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分子量
- 11.5 kDa (Monomer), 90 kDa (Heteromer)
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基因ID
- 7341
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UniProt
- P63165
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途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
抗原
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