STAT2 抗体
Quick Overview for STAT2 抗体 (ABIN7659945)
抗原
See all STAT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- STAT2(STAT2/2650)
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产品特性
- Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human STAT2 protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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别名
- STAT2
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背景
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Synonyms: Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator (ISGF3), P113, signal transducer and activator of transcription 2 113kD (STAT113), Signal transducer and activator of transcription 2 (STAT2)
Gene Symbol: STAT2
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分子量
- 113 kDa
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基因ID
- 6773
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UniProt
- P52630
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途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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