ROR2 抗体
Quick Overview for ROR2 抗体 (ABIN7659450)
抗原
See all ROR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ROR2(ROR2/1912)
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产品特性
- ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt-1 and Wnt-3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1, or the autosomal recessive skeletal disorder, Robinow syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human cultured keratinocytes
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亚型
- IgG
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anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 683-934) antibody
ROR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 59-155) antibodyROR2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F2D10 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50), (N-Term) antibodyROR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01507-01508 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50) antibodyROR2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 752-926) antibodyROR2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 915-943), (C-Term) antibodyROR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01510 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (Internal Region) antibodyROR2 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-143) antibodyROR2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E1 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) antibodyROR2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ROR2-1911 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 100-200) antibodyROR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Human breast, pancreas, kidney or GIST.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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别名
- ROR2
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背景
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Synonyms: BR, CD49 antigen-like family member B, ROR2, Collagen receptor, DX5, Glycoprotein Ia deficiency included (GPIa), Human platelet alloantigen system 5 (HPA5 included), Integrin alpha II (ITGA2), Platelet alloantigen Br(a), included, Platelet glycoprotein Ia/IIa, Platelet membrane glycoprotein Ia, VLA2,
Gene Symbol: ROR2
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分子量
- 120 kDa
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基因ID
- 4920
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UniProt
- Q01974
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途径
- RTK signaling, WNT signaling
抗原
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