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PMEPA1 抗体 (CF®640R)

This CF®640R-conjugated 小鼠 单克隆 anti-PMEPA1 antibody (Clone PMEPA1-2696) specifically detects PMEPA1 in IHC 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7659301
发货至: 中国
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Quick Overview for PMEPA1 抗体 (CF®640R) (ABIN7659301)

抗原

See all PMEPA1 抗体
PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PMEPA1 antibody is conjugated to CF®640R

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

PMEPA1-2696
  • 原理

    PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2696), CF640R conjugate

    产品特性

    PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human PMEPA1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Human prostate, breast or renal cell carcinoma tissue (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

    别名

    PMEPA1

    背景

    Synonyms: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

    Gene Symbol: PMEPA1

    Tissue Expression: Kidney|Ovary|Prostate

    分子量

    32 kDa

    基因ID

    56937

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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