PMEPA1 抗体 (CF®405S)
Quick Overview for PMEPA1 抗体 (CF®405S) (ABIN7659300)
抗原
See all PMEPA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2698), CF405S conjugate
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产品特性
- PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human PMEPA1 protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Human prostate, breast or renal cell carcinoma tissue (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
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别名
- PMEPA1
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背景
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Synonyms: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA
Gene Symbol: PMEPA1
Tissue Expression: Kidney|Ovary|Prostate
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分子量
- 32 kDa
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基因ID
- 56937
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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