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Recombinant Prostate Specific Antigen 抗体 (CF®405S)

This anti-Prostate Specific Antigen antibody is a 兔 单克隆 antibody detecting Prostate Specific Antigen in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7659241
发货至: 中国

Quick Overview for Recombinant Prostate Specific Antigen 抗体 (CF®405S) (ABIN7659241)

抗原

See all Prostate Specific Antigen (PSA) 抗体
Prostate Specific Antigen (PSA)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Prostate Specific Antigen antibody is conjugated to CF®405S

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

KLK3-2871R
  • 原理

    Prostate Specific Antigen (PSA) (KLK3/2871R), CF405S conjugate

    产品特性

    This antibody recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human KLK3 protein

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1.0 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA pH 9.0 for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: PC12 cells or normal prostate or prostate carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Prostate Specific Antigen (PSA)

    别名

    Prostate Specific Antigen

    背景

    Synonyms: Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin

    Gene Symbol: KLK3

    分子量

    33-34 kDa

    基因ID

    354

    UniProt

    P07288

    途径

    Complement System
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