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PODXL 抗体 (AA 310-447)

This anti-PODXL antibody is a 小鼠 单克隆 antibody detecting PODXL in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7658753
发货至: 中国

Quick Overview for PODXL 抗体 (AA 310-447) (ABIN7658753)

抗原

See all PODXL 抗体
PODXL (Podocalyxin-Like (PODXL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PODXL antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

PODXL-2185
  • 抗原表位

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    AA 310-447

    原理

    Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) (PODXL/2185)

    产品特性

    Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is highly expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment of human Podocalyxin (around aa 310-447)

    亚型

    IgG1
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: HeLa, Raji, Jurkat cells, Angiosarcoma, Breast, Prostate, Liver, Pancreatic, Kidney

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    PODXL (Podocalyxin-Like (PODXL))

    别名

    Podocalyxin

    背景

    Synonyms: PODXL, PDXL, GCTM-2, Gp200, PCLP1, Pcx, Podocalyxin-like protein 1

    Gene Symbol: PODXL

    Tissue Expression: Kidney

    分子量

    165-170 kDa

    基因ID

    5420

    UniProt

    O00592

    途径

    Tube Formation
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