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PODXL 抗体 (AA 310-447) (CF®405S)

This anti-PODXL antibody is a 小鼠 单克隆 antibody detecting PODXL in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7658735
发货至: 中国

Quick Overview for PODXL 抗体 (AA 310-447) (CF®405S) (ABIN7658735)

抗原

See all PODXL 抗体
PODXL (Podocalyxin-Like (PODXL))

适用

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宿主

  • 68
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小鼠

克隆类型

  • 70
  • 54
单克隆

标记

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This PODXL antibody is conjugated to CF®405S

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

PODXL-2184
  • 抗原表位

    • 22
    • 17
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    AA 310-447

    原理

    Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker)(PODXL/2184), CF405S conjugate

    产品特性

    Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment of human Podocalyxin (around aa 310-447)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa, Raji, Jurkat cells, Angiosarcoma, Breast, Prostate, Liver, Pancreatic, Kidney

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    PODXL (Podocalyxin-Like (PODXL))

    别名

    Podocalyxin

    背景

    Synonyms: PODXL, PDXL, GCTM-2, Gp200, PCLP1, Pcx, Podocalyxin-like protein 1

    Gene Symbol: PODXL

    Tissue Expression: Kidney

    分子量

    165-170 kDa

    基因ID

    5420

    UniProt

    O00592

    途径

    Tube Formation
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