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CD31 抗体 (AA 625-738) (CF®568)

This 小鼠 单克隆 antibody specifically detects CD31 in WB, IHC 和 IHC (fp). It exhibits reactivity toward 人.
产品编号 ABIN7658662
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD31 抗体 (AA 625-738) (CF®568) (ABIN7658662)

抗原

See all CD31 (PECAM1) 抗体
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD31 antibody is conjugated to CF®568

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

PECAM1-3528
  • 抗原表位

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    AA 625-738

    原理

    CD31 / PECAM-1 (Endothelial Cell Marker)(PECAM1/3528), CF568 conjugate

    产品特性

    CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (around aa 625-738) of human CD31 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Jurkat cells. Tonsil or Angiosarcoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    别名

    CD31

    背景

    Synonyms: EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA

    Gene Symbol: PECAM1

    Tissue Expression: Endothelial cells

    分子量

    ~100 kDa (endothelium) and ~130 kDa (platelets)

    基因ID

    5175

    UniProt

    P16284

    途径

    Regulation of Actin Filament Polymerization
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