Recombinant Nkx2-2 抗体 (CF®740)
Quick Overview for Recombinant Nkx2-2 抗体 (CF®740) (ABIN7657950)
抗原
See all Nkx2-2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF740 conjugate
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产品特性
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human full-length recombinant NKX2.2 protein
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亚型
- IgG2b, kappa
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anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibody
Nkx2-2 适用: 人 IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal NX2-1524 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal NX2-1523 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, 小鸡 IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal NX2-294 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) (N-Term) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, 小鸡 IHC, StM 宿主: 小鼠 Monoclonal rNX2-294 unconjugated Recombinant Antibody
anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 兔 Monoclonal NX2-2198R unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 兔 Monoclonal NX2-1422R unconjugated Recombinant Antibody
anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rNX2-1523 unconjugated Recombinant Antibody
anti-NK2 Homeobox 2 (Nkx2-2) (N-Term) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Immunohistology (formalin): 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Pancreas or Ewing s sarcoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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别名
- NKX2.2
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背景
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Synonyms: Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
Gene Symbol: NKX2-2
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分子量
- 40-50 kDa
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基因ID
- 4821
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UniProt
- O95096
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途径
- Dopaminergic Neurogenesis
抗原
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