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Nkx2-2 抗体 (AA 1-119) (CF®640R)

This anti-Nkx2-2 antibody is a 兔 单克隆 antibody detecting Nkx2-2 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7657937
发货至: 中国

Quick Overview for Nkx2-2 抗体 (AA 1-119) (CF®640R) (ABIN7657937)

抗原

See all Nkx2-2 抗体
Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

适用

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  • 6
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  • 5
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  • 2
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宿主

  • 75
  • 61

克隆类型

  • 87
  • 49
单克隆

标记

  • 60
  • 12
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  • 7
  • 7
  • 7
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  • 2
  • 1
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This Nkx2-2 antibody is conjugated to CF®640R

应用范围

  • 75
  • 50
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  • 34
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  • 23
  • 13
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  • 8
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  • 3
  • 2
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

NX2-2198R
  • 抗原表位

    • 38
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-119

    原理

    NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(NX2/2198R), CF640R conjugate

    产品特性

    Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human NKX2.2 protein fragment (around aa1-119)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Pancreas or Ewing sarcoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

    别名

    NKX2.2

    背景

    Synonyms: Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman

    Gene Symbol: NKX2-2

    分子量

    40-50 kDa

    基因ID

    4821

    UniProt

    O95096

    途径

    Dopaminergic Neurogenesis
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