Nkx2-2 抗体 (AA 1-119) (CF®405S)
Quick Overview for Nkx2-2 抗体 (AA 1-119) (CF®405S) (ABIN7657934)
抗原
See all Nkx2-2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            抗原表位
- AA 1-119
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                                            原理
- NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(NX2/2198R), CF405S conjugate
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                                            产品特性
- Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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                                            免疫原
- Recombinant human NKX2.2 protein fragment (around aa1-119)
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                                            亚型
- IgG
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
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                                            说明
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                        Positive Control: Pancreas or Ewing sarcoma 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 0.1 mg/mL
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                                            缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Protect from light
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                                            储存条件
- 4 °C
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                                            储存方法
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                        Stable at room temperature or 37°C for 7 days. Protect from light Store at 2 to 8°C. Protect fluorescent conjugates from light 
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                                            有效期
- 24 months
 
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    - Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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                                            别名
- NKX2.2
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                                            背景
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                        Synonyms: Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman Gene Symbol: NKX2-2 
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                                            分子量
- 40-50 kDa
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                                            基因ID
- 4821
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                                            UniProt
- O95096
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                                            途径
- Dopaminergic Neurogenesis
 抗原
- 
                    
 
                                     
                                     
                                    