NADPH Oxidase 4 抗体 (CF®740)
Quick Overview for NADPH Oxidase 4 抗体 (CF®740) (ABIN7657692)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NOX4 / NADPH Oxidase 4 (NOX4/1245), CF740 conjugate
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产品特性
- The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human NOX4 protein
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亚型
- IgG2b, kappa
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anti-NADPH Oxidase 4 (NOX4) (AA 210-310) antibody
NOX4 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3H2G11 unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 328-578) antibodyNOX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 220-392) antibodyNOX4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 81-180) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IP, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 210-424) antibodyNOX4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 561-578), (C-Term) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 124-153), (N-Term) antibodyNOX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34043 unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 124-153) antibodyNOX4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (C-Term) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 201-300) antibodyNOX4 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: PC-12, JAR cells. Kidney
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- NADPH Oxidase 4 (NOX4)
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别名
- NADPH-Oxidase-4
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背景
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Synonyms: Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, NADPH oxidase 4, Nox4, Renal NAD(P)H-oxidase, RENOX
Gene Symbol: NOX4
Tissue Expression: Endothelial cells|Kidney
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分子量
- 70 kDa
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基因ID
- 50507
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UniProt
- Q9NPH5
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途径
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
抗原
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