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MUC5AC 抗体 (CF®740)

This anti-MUC5AC antibody is a 小鼠 单克隆 antibody detecting MUC5AC in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7657438
发货至: 中国

Quick Overview for MUC5AC 抗体 (CF®740) (ABIN7657438)

抗原

See all MUC5AC 抗体
MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

适用

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小鼠

克隆类型

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单克隆

标记

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This MUC5AC antibody is conjugated to CF®740

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CLH2
  • 原理

    Mucin 5AC (MUC5AC)(CLH2), CF740 conjugate

    产品特性

    Mucin 5AC glycoprotein (MUC5AC) is a HMW glycoprotein belonging to the superfamily of mucins. Mucins are produced by epithelial cells and can be divided into two families, secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming, secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A synthetic peptide of human MUC5AC tandem repeat

    亚型

    IgG1, kappa
  • 应用备注

    Immunohistology formalin-fixed 1-2 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Immunofluorescence 1-2 μg/mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: Stomach

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

    别名

    Mucin 5AC

    背景

    Synonyms: Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)

    Gene Symbol: MUC5AC

    Tissue Expression: Epithelial cells

    分子量

    >1,000 kDa

    基因ID

    4586

    UniProt

    P98088
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