LSP1 抗体 (AA 174-278) (CF®405S)
Quick Overview for LSP1 抗体 (AA 174-278) (CF®405S) (ABIN7656427)
抗原
See all LSP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 174-278
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原理
- Lymphocyte Specific Protein 1 (LSP1) / pp52(LSP1/3042), CF405S conjugate
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产品特性
- LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15. 5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human LSP1 protein (around aa174-278)
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亚型
- IgG1, kappa
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anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 174-278) antibody
LSP1 适用: 人 IHC, IHC (p), StM 宿主: 小鼠 Monoclonal LSP1-3025 unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) antibodyLSP1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 241-339) antibodyLSP1 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 127-331) antibodyLSP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (C-Term) antibodyVerified LSP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 240-338) antibodyLSP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 1-339) antibodyLSP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 108-134) antibodyLSP1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20589 unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (pSer204) antibodyLSP1 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 1-339) antibodyLSP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Human tonsil, colon, spleen or Hodgkin lymphoma (IHC-P).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- LSP1 (Lymphocyte-Specific Protein 1 (LSP1))
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别名
- Lymphocyte Specific Protein 1
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背景
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Synonyms: WP34, pp52, lymphocyte specific protein 1, leukocyte specific protein 1
Gene Symbol: LSP1
Tissue Expression: Leukocytes
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分子量
- 52 kDa
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基因ID
- 4046
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UniProt
- P33241
抗原
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