Recombinant GRP94 抗体
Quick Overview for Recombinant GRP94 抗体 (ABIN7654861)
抗原
See all GRP94 (HSP90B1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GRP94 / HSP90B1(Glucose-Regulated Protein 94) (Endoplasmic Reticulum Marker)(HSP90B1/3168R)
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产品特性
- Recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been studied as a prognostic factor in breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human HSP90B1 protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HepG2, U20S cells. About 50% of breast tumors express grp94 protein.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
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别名
- GRP94
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背景
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Synonyms: Glucose Regulated Protein 94, 94 kDa glucose-regulated protein, Endoplasmin, Endothelial cell (HBMEC) glycoprotein (ECGP), Heat shock protein 90 kDa beta member 1 (HSP90B1), Stress inducible tumor rejection antigen GP96, TRA1, Tumor rejection antigen-1 (gp96)
Gene Symbol: HSP90B1
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分子量
- 94 kDa
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基因ID
- 7184
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UniProt
- P14625
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途径
- Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
抗原
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