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GRP94 抗体 (Middle Region)

Name: GRP94 抗体 (Middle Region)
SKU: ABIN3044299
Availability: OutOfStock

HSP90B1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Anti-GRP94 antibody, Western blotting Lane 1: RAJI Cell Lysate Lane 2: MCF-7 Cell Lysate

Anti-GRP94 antibody, IHC(P) IHC(P): Rat Brain Tissue

IHC

Anti-GRP94 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue

IHC

Anti-GRP94 antibody, IHC(P) IHC(P): HELA Cell

IHC

4 images

(1 reference)

产品编号 ABIN3044299

发货至: 中国

Datasheet as PDF

抗原 See all GRP94 (HSP90B1) 抗体

GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
抗原表位
21

19

16

7

7

7

7

7

6

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 687-700, Middle Region
适用
133

86

55

40

35

31

30

30

28

28

26

26

25

17

10

2

2

1

1
人, 小鼠, 大鼠
宿主
93

40

24

2

1
兔
Compatible Secondaries
克隆类型
94

66
多克隆
标记
70

12

11

11

10

8

4

4

4

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GRP94 antibody is un-conjugated
应用范围
152

83

69

63

49

46

39

21

13

13

12

11

4

4

2

2

1
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Rabbit IgG polyclonal antibody for Endoplasmin(HSP90B1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

序列

INPRHPLIRD MLRR

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Endoplasmin(HSP90B1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: heat shock protein 90 kDa beta(Grp94), member 1
Protein Name: Endoplasmin

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human GRP94(687-700aa INPRHPLIRDMLRR), identical to the related mouse and rat sequences.

亚型

IgG

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anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 550-650) antibody
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anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (Center) antibody
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anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (C-Term) antibody
HSP90B1 适用: 人, 小鼠, 大鼠 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (Internal Region) antibody
Verified HSP90B1 适用: 人, 小鼠 WB, IHC, IF, FACS, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 676-803) antibody
HSP90B1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 2H3 unconjugated

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) antibody
HSP90B1 适用: 人, 小鼠, 大鼠, Cow, 小鸡, Hamster, 犬, 兔, Pig, 豚鼠, 猴, 绵羊, 马, 非洲爪蟾 WB, IHC, IF, FACS, StM 宿主: 大鼠 Monoclonal 9G10-F8-2 unconjugated

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) antibody
HSP90B1 适用: 人, 小鼠, 大鼠, Cow, 小鸡, Hamster, 犬, 兔, Pig, 豚鼠, 猴, 绵羊, 马, 非洲爪蟾 IHC, FACS, StM 宿主: 兔 Monoclonal HSP90B1-3168R unconjugated Recombinant Antibody

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (C-Term) antibody
HSP90B1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) antibody
HSP90B1 适用: 人 WB, IHC, IF, IP, ELISA 宿主: 小鼠 Monoclonal H9010 unconjugated

anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) antibody
HSP90B1 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2H3 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
Wang, Wang, Huang, Yang, Zhao, Wei, Zhao: "Erratum to: Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." in: Heart and vessels, Vol. 32, Issue 2, pp. 216, (2016) (PubMed).
抗原

GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

别名

HSP90B1 (HSP90B1 产品)

别名

ecgp antibody, gp96 antibody, tra1 antibody, grp94 antibody, DDBDRAFT_0206450 antibody, DDBDRAFT_0215015 antibody, DDB_0206450 antibody, DDB_0215015 antibody, TRA1 antibody, HSP90B1 antibody, ERp99 antibody, GRP94 antibody, TA-3 antibody, Targ2 antibody, Tra-1 antibody, Tra1 antibody, endoplasmin antibody, GP96 antibody, fb61d09 antibody, tra-1 antibody, wu:fb61d09 antibody, wu:fq25g01 antibody, Grp94 antibody, ECGP antibody, Gp96 antibody, ppk98 antibody, hsp108 antibody, heat shock protein 90kDa beta (Grp94), member 1 antibody, heat shock protein Hsp90 family protein antibody, 94 kD glucose-regulated protein antibody, heat shock protein 90 beta family member 1 antibody, heat shock protein 90, beta (Grp94), member 1 antibody, heat shock protein 90, beta (grp94), member 1 antibody, heat shock protein 90kDa beta family member 1 L homeolog antibody, hsp90b1 antibody, grp94 antibody, HSP90B1 antibody, Hsp90b1 antibody, hsp90b1.L antibody

背景

Heat shock protein 90 kDa beta member 1 (HSP90B1), known also as endoplasmin, GRP94, is a chaperone protein that in humans is encoded by the HSP90B1 gene. It is mapped to chromosome 12q23.3. This gene encodes a member of a family of adenosine triphosphate (ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation.

Synonyms: 94 kDa glucose regulated protein antibody|94 kDa glucose-regulated protein antibody|ECGP antibody|Endoplasmin antibody|Endothelial cell(HBMEC) glycoprotein antibody|ENPL_HUMAN antibody|Glucose regulated protein 94 antibody|Glucose regulated protein 94 kDa antibody|gp96 antibody|gp96 homolog antibody|GRP 94 antibody|GRP-94 antibody|Heat shock protein 90 kDa beta member 1 antibody|heat shock protein 90 kDa beta(Grp94), member 1 antibody|Heat shock protein, 90 kDa, beta, 1 antibody|HSP90B1 antibody|Stress inducible tumor rejection antigen GP96 antibody|TRA1 antibody|tumor rejection antigen(gp96) 1 antibody|Tumor rejection antigen 1 antibody|Tumor rejection antigen gp96 antibody|Tumor rejection antigen-1(gp96) antibody

UniProt

P14625

途径

Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades