电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant CD3 epsilon 抗体 (Extracellular Domain)

The 兔 单克隆 anti-CD3 epsilon antibody is suitable to detect CD3 epsilon in samples from 人. It has been validated for WB, IHC 和 IHC (fp).
产品编号 ABIN7651250
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD3 epsilon 抗体 (Extracellular Domain) (ABIN7651250)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

抗体类型

Recombinant Antibody

适用

  • 452
  • 230
  • 50
  • 49
  • 21
  • 20
  • 7
  • 7
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 274
  • 217
  • 44
  • 39
  • 34
  • 11
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1

克隆类型

  • 504
  • 120
  • 8
  • 3
单克隆

标记

  • 270
  • 44
  • 38
  • 35
  • 32
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 9
  • 8
  • 8
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD3 epsilon antibody is un-conjugated

应用范围

  • 384
  • 252
  • 205
  • 128
  • 126
  • 118
  • 52
  • 50
  • 34
  • 31
  • 27
  • 21
  • 21
  • 14
  • 13
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

C3e-2858R
  • 抗原表位

    • 78
    • 40
    • 27
    • 20
    • 16
    • 16
    • 14
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-119, Extracellular Domain

    原理

    CD3e (T-Cell Marker)(C3e/2858R)

    产品特性

    The immunogen for this Mab is derived from the extracellular domain of CD3 epsilon chain. CD3 consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human CD3e extracellular domain fragment (around aa 23-119)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Jurkat cells. Tonsil and lymph node

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, no BSA, no azide

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at -20 °C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3e

    背景

    Synonyms: CD3 epsilon, CD3 TCR complex, CD3e antigen epsilon polypeptide (TiT3 complex), T cell antigen receptor complex epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E

    Gene Symbol: CD3E

    Tissue Expression: T-cells

    分子量

    20 kDa

    基因ID

    916

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
You are here: